Too few people donate their organs, dead or alive. How can we make it easier to donate, but avoid the abuses that some fear from cash payments?

I was deliberately infected with Zika to test a vaccine. Human challenge trials like my one could save millions of lives by developing prophylactics more quickly.

Homeowners are often the biggest opponents of building new homes. An Israeli reform reversed this by making homeowners the main beneficiaries of development.

We used to dig up roads to put trains underneath – cheaply. Ever-better tunnel boring machines have made the disruption this causes unnecessary.

Silk is stronger than steel or kevlar. We are already using it to transport vaccines without cold chains and make automatically dissolving stitches. What else could it be used for?

SGLT2, a protein in the kidney, takes glucose out of the urine and puts it in the blood. Blocking this reduces diabetes, heart disease, and kidney disease – but we’re not exactly sure why.